819 Mouse anti-human CD62 (P-selectin) monoclonal antibody, clone CRC81 1 ml

In Stock

315 USD

Article Number: 819

Monoclonal antibody anti-human CD62 (P-selectin, GMP 140, PADGEM) (clone CRC81, IgG1 kappa fraction)


Specificity

Reacts with CD62 antigen (P-selectin, integral membrane sialoglycoprotein 140 kDa, GMP-140, granule membrane protein 140, PADGEM), which is expressed in platelet alpha granules that are translocated to the platelet surface upon activation with strong agonists. A similar protein, present in endothelial cell Weibel-Palade bodies, is transiently expressed on the surface of activated endothelial cells and functions as adhesion molecule for granulocytes. The antibody does not interfere with the functional activity of CD62 as an adhesion receptor for neutrophils


Preparation

Ammonium sulphate precipitation and DEAE-cellulose chromatography with gradient elution


Format

Purified and lyophilized. Contains azide and PBS. The azide concentration in reconstituted solution is 3 mM


Applications

Immunofluorescence (indirect). Detection of activated platelets. Recommended dilution x100


Reconstitution

Use 1 ml sterile pure water


Storage

Shipping at ambient temperature. Storage of lyophilized antibodies 2 years at -20°C or lower