210 Collagen type II (human) 0.1 mg

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195 USD

Article Number: 210

Collagen Type II protein purified from human cartilage


Source

Human cartilage. Negative for HBsAg, HCV, HIV1 and HIV2


Purity

Human collagen type II > 95%, human collagen types I and III < 5%, other human collagen types and non-collagen proteins < 0.5%.


Format

Lyophilized


Purification

Partial pepsin digestion in acidic conditions and differential salt precipitation


Applications

Standard for immunological assays. Antigen for immunisation (1) and antibody production. Coating material for cell culture studies. 


Reconstitution

Use 0.5 M acetic acid, pH 2.5


Storage

Shipping at ambient temperature. Storage 2 years at -20°C or lower


Citations

1. Gualandi L, Kamath R, Schwartz Sterman A (2014) Anti-collagen antibodies for treatment and diagnosis. US20170226196A1 patent application

2. Pal S, V. Badireenath Konkimalla (2016) Data on sulforaphane treatment mediated suppression of autoreactive, inflammatory M1 macrophages. Data in Brief. https://doi.org/10.1016/j.dib.2016.03.105

3. Rezaei N, Lyons A, Forde NR (2018) Environmentally controlled curvature of single collagen proteins. bioRxiv  http://dx.doi.org/10.1101/279380